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Combining nifedipine with alprazolam produced additional antidepressant effects, which indicates that they exert antidepressant effects through different mechanisms. Ampicillin and Cloxacillin were used for treatment of aspiration pneumonia. In this model, mice are forced to swim in a restricted space from which there is no escape. The mouse FST model has been widely used in screening antidepressants because it is simple and has been reported to be reliable across laboratories.
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